BioEnthesis®

A BIPHASIC INTERPOSITIONAL ALLOGRAFT FOR ROTATOR CUFF REPAIR
the first-of-its-kind
biphasic interpositional
allograFt FOR rotator cuff repair
Why Cancellous Bone is Better than Cortical Bone
Why Cancellous Bone is Better than Cortical Bone
Learn now

Clinical Challenge

Too many rotator cuff repairs result in re-tear. Why? Healing relies on reincorporation of tendon into the bone at the enthesis. See what the literature says about the enthesis:

The Enthesis: A Review of the Tendon-to-Bone Insertion

(Apostolakos et al, 2014)

The “Enthesis Organ” Concept — Why Enthesopathies May Not Present as…

(Benjamin et al, 2004)

Enthesis Repair: Challenges and Opportunities for Effective Healing

(Darwin et al, 2018)

Assembly, Maturation, and Degradation of the Supraspinatus Tendon

(Jensen et al, 2018)

Current Progress in Tendon and Ligament Tissue Engineering

(Lim et al, 2019)

Orthopedic Repair Strategies Based on Native Features of the Multiscale Enthesis

(Locke et al, 2017)

Tendon Augmentation Grafts: A Systematic Review

(Longo et al, 2010)

Classification of Tendon Matrix Change Using Ultrasound: A Systematic Review

(Matthews et al, 2018)

Mineral Distributions at the Developing Tendon Enthesis

(Schwartz et al, 2012)

Muscle-Tendon-Enthesis Unit (Function, Failure, and Imaging)

(Tadros et al, 2018)

The Interfascicular Matrix Enables Fascicle Sliding and Recovery in Tendon…

(Thorpe et al, 2015)

B.U.C. THE TREND OF ROTATOR CUFF RE-TEAR
WITH BIOENTHESIS UNDER THE CUFF.

BACKED BY SCIENCE
OUTSTANDING CLINICAL PROFILE
PUBLICATION PENDING; DATA AVAILABLE UPON REQUEST
Sharpey fiber formation +
reduced inflammation
in ovine model.
Despite significantly older patients, BioEnthesis showed fewer retears and significantly better MRIs.

Publications

Case video

Dr. Alan Reynolds
(Wake Forest Baptist Health)

Paper

Indications and Technique: Rotator Cuff Repair Augmentation
(Yanke et al, 2023)

Case video

    Dr. Brian Forsythe (Midwest Orthopedics at Rush, Chicago, IL)

Paper

Ovine Study Editorial Commentary
(Dr. Andrew Sheean)

Talk

Dr. Shariff Bishai
(Detroit Orthopedic Institute, Detroit, MI)

Paper

Indications and Technique: Rotator Cuff Repair Augmentation
(Yanke et al, 2023)

Indication for Use:

BioEnthesis is indicated to provide a matrix for the repair or reconstruction of the bone of the enthesis within the rotator cuff.

Contraindications:

BioEnthesis is contraindicated for use in any patient in whom soft and hard tissue implants are contraindicated. This includes any pathology that would limit the blood supply and compromise healing, or evidence of a current infection. BioEnthesis is contraindicated where the allograft is intended as structural support in load-bearing bone, and articular cartilage surfaces.

INOVA Patient Set

Set of 2 patients out of the Northern Virginia area with postoperative scores and MRIs
01-01
07.11.2025
3 years 6 mo
Date of Research Visit
07.11.2025
Active Forward Flexion
170
Passive Forward Flexion
170
External Rotation at Side
60
Supraspinatus Test
5/5
Infraspinatus Test
5/5
Subscapularis Test
5/5
ASES Score
78
VR-12 Physical Score
61,834183
VR-12 Mental Score
43,539505
How would you rate your shoulder today as a percentage of normal?
90
How would you rate your opposite shoulder as a percentage of normal?
90
01-02
07.14.2025
3 years 8 mo
Date of Research Visit
07.14.2025
Active Forward Flexion
170
Passive Forward Flexion
170
External Rotation at Side
60
Supraspinatus Test
5/5
Infraspinatus Test
5/5
Subscapularis Test
5/5
ASES Score
77
VR-12 Physical Score
64,186441
VR-12 Mental Score
33,052378
How would you rate your shoulder today as a percentage of normal?
80
How would you rate your opposite shoulder as a percentage of normal?
100